Daim Ntawv Thov Tseem Ceeb Scenarios
AICAR tuav tus nqi tseem ceeb hauv kev tshawb fawb biomedical:
Kev Tshawb Fawb Txog Metabolic: AICAR yog ib qho cuab yeej cuab tam rau kev kawm AMPK txoj kev taw qhia, nquag siv los tshawb txog cov txheej txheem tswj hwm ntawm lipid metabolism, qabzib metabolism, thiab cellular zog homeostasis.
Stem Cell Research: Cov kev tshawb fawb qhia tias AICAR upregulates qhov kev qhia ntawm pluripotency -cov noob caj noob ces (xws li Klf4, Nanog, Oct4, thiab Sox2) nyob rau hauv nas embryonic qia hlwb thiab inhibits retinoic acid-induced sib txawv; Nws kuj txhawb kev sib txawv osteogenic thaum inhibiting adipogenic sib txawv hauv mesenchymal qia hlwb.
Neuroscience: AICAR inhibits qhov kev loj hlob ntawm neural qia hlwb thiab ua rau muaj kev sib txawv rau hauv astrocytes, ua ib qho cuab yeej tseem ceeb rau kev tshawb fawb txog kev tsim kho neurodevelopment.
Kev Cuam Tshuam Physiology thiab Endurance Research: Ib txoj kev tshawb fawb keeb kwm luam tawm hauv * Cell * hauv xyoo 2008 tau pom tias cov nas nyob hauv tsev kho mob nrog AICAR rau plaub lub lis piam pom tau tias 44% nce hauv kev ua siab ntev piv rau pawg tswj hwm; lawv cov leeg nqaij gene qhia cov ntaub ntawv zoo ib yam li cov leeg nqaij uas tau txais kev cob qhia- qhov kev tshawb pom uas tau txais kev saib xyuas thoob plaws hauv cov zej zog kev kawm thiab kis las.
Cov txiaj ntsig muaj peev xwm hauv kev tsim lub cev
AICAR tau nyiam cov kev txaus siab hauv kev tsim lub cev thiab kev ua kom zoo ntawm lub cev feem ntau vim nws lub luag haujlwm tshwj xeeb hauv kev ua kom txoj hauv kev AMPK:
Kev txhawb nqa ntawm Fatty Acid Oxidation: AMPK kev ua kom yooj yim txhawb nqa thiab oxidation ntawm fatty acids hauv cov leeg pob txha, pab txo lub cev rog thiab txhim kho lub cev muaj pes tsawg leeg.
Insulin-Kev ywj pheej Glucose Uptake: AICAR txhawb nqa cov piam thaj hauv cov leeg pob txha los ntawm cov tshuaj insulin- txoj kev ywj pheej. Cov txheej txheem no ua haujlwm ntawm nws tus kheej ntawm PI3K txoj hauv kev, muab txoj hauv kev rau kev tswj hwm cov piam thaj hauv cov metabolism uas txawv ntawm cov tshuaj insulin ib txwm muaj -sensitizing agents.
Mimicking Exercise Effects: AICAR tuaj yeem "trick" cov leeg rau hauv kev tsim cov cim molecular cuam tshuam nrog kev ua haujlwm ntawm lub cev thiab ua kom cov noob muaj feem xyuam rau oxidative metabolism; Raws li txoj cai, qhov no tuaj yeem pab tswj kev hloov pauv hauv metabolic thaum lub sijhawm kawm.
Nws yog ib qho tseem ceeb uas yuav tsum nco ntsoov tias tam sim no tsis muaj cov ntaub ntawv soj ntsuam kuaj mob txog AICAR qhov cuam tshuam rau tib neeg kev ua kis las; Cov pov thawj uas twb muaj lawm yog muab los ntawm cov tsiaj sim thiab * hauv vitro * kev tshawb fawb. Lub Ntiaj Teb Kev Tiv Thaiv -Doping Agency (WADA) ntxiv AICAR rau nws Daim Ntawv Teev Tseg hauv 2009. Cov Lus Qhia Siv:
Rov ua dua siv cov dej tsis huv rau kev txhaj tshuaj lossis ib qho tsis haum; vortex maj mam thiab tsis txhob muaj zog co los tiv thaiv foaming.
Aliquot rau hauv ib qho - siv cov ntu tom qab rov tsim kho kom tsis txhob muaj kev poob haujlwm los ntawm kev rov ua kom khov dua - thaw cycles.
Siv kom sai li sai tau tom qab qhib los tiv thaiv kev kis kab mob thiab degradation.
Hnav hnab looj tes thoob plaws hauv cov txheej txheem thiab ua raws li cov txheej txheem kuaj biosafety.
Vim Li Cas Xaiv Peb
Cov Chaw Tsim Khoom Ncaj Ncees nrog Nqe Zoo: Peb ua haujlwm ntawm peb tus kheej cov chaw tsim khoom tsis muaj cov neeg nruab nrab, cia peb tswj cov nqi thiab qhov zoo ntawm qhov chaw; tus nqi sib tw heev rau kev txiav txim ntau.
Cov Khoom Siv Tsim Khoom: Nruab nrog cov khoom siv siab heev-theem peptide synthesis (SPPS) kab, siab -kev ua haujlwm ua kua chromatography (HPLC) purification systems, thiab khov- cov cuab yeej ziab kom ua kom zoo ib yam rau txhua pawg.
Cov khoom siv ruaj khov: Cov khoom siv raw khoom txaus thiab lav muaj peev xwm ntau lawm; nyob rau hauv -Tshuaj muaj rau cov khoom txheem thiab cov sij hawm ua cov hmoov lead ntshiab rau cov khoom siv; cog lus rau ntev -lub sij hawm, ruaj khov kev koom tes.
High Purity Guarantee: Txhua batch tau kuaj dual ntawm HPLC thiab huab hwm coj spectrometry (MS), ua tiav qib purity ntau dua 98%; Daim ntawv pov thawj ntawm Kev Ntsuam Xyuas (COA) yog muab nrog cov khoom xa tuaj.
Kev Ua Tau Zoo: Kev ua raws li cov txheej txheem tsim khoom tsim nyog thiab kev tswj hwm cov txheej txheem ua kom cov khoom siv tsawg kawg nkaus - mus rau - batch variation thiab txhim khu kev qha cov ntaub ntawv tshawb fawb.
Kev txhawj xeeb-Dawb Tom Qab- Kev Pabcuam Muag: Ib pab pawg kws tshaj lij muab kev sib tham ua ntej- muag thiab tom qab- kev txhawb nqa muag; kev xa rov qab los yog kev sib pauv yog lav rau cov teeb meem zoo, ua kom xoom- pheej hmoo yuav khoom rau cov neeg siv khoom.
FAQ
Q: Koj cov khoom tsim nyob qhov twg?
A: Peb cov khoom tsim nyob rau hauv Shenzhen, Suav.
Q: Qhov kev txiav txim yam tsawg kawg nkaus (MOQ) yog dab tsi?
A: Yam tsawg kawg nkaus kom muaj nuj nqis yog 10 vials / teeb.
Q: Koj yuav nkoj sai npaum li cas?
A: Kev txiav txim rau hauv - cov khoom xa tuaj hauv 24 teev.
Q: Dab tsi purity theem koj muab?
A: Tus qauv purity yog 99%.
Q: Yam khoom thauj twg koj siv?
A: Cov kev xaiv suav nrog FedEx, DHL, UPS, thiab kev pabcuam xa ntawv.
Q: Ntev npaum li cas shipping?
A: Kwv yees li 10-15 hnub.
Q: Koj puas muab COA thiab HPLC cov ntawv xeem?
A: Yog, cov no tau muab; tag nrho cov khoom raug kuaj xyuas ua ntej ua zaub mov xa tuaj.
Q: Koj puas muab kev pabcuam OEM / tus kheej daim ntawv lo?
A: Yog, OEM / private labeling cov kev pabcuam muaj, raws li qhov yuav tsum tau ua kom tsawg kawg nkaus. Q: Yuav ua li cas tom qab- cov teeb meem kev muag khoom tau daws?
A: Yog tias, tom qab tus neeg siv khoom tau txais cov khoom, qhov teeb meem zoo tau lees paub tias muaj keeb kwm los ntawm peb cov txheej txheem tsim khoom, tus neeg siv khoom tsim nyog rau kev hloov pauv dawb lossis nyiaj rov qab. Peb txhawb nqa lub tswv yim ua haujlwm zoo thiab lub luag haujlwm, ua haujlwm zoo thiab daws txhua yam teeb meem; peb tsis ua lub luag haujlwm lossis tshem tawm cov teeb meem, thiab peb tau cog lus tias yuav tiv thaiv peb cov neeg siv khoom txoj cai thiab kev txaus siab.
Q: Txoj kev them nyiaj twg muaj?
A: Peb lees txais kev hloov pauv hauv txhab nyiaj, Bitcoin, TransferWise, thiab Xoom.
Cim npe nrov: AICAR (50 mg / vial) rau kev siv oncology thiab qabzib / lipid metabolism (CAS: 2627-69-2), Tuam Tshoj AICAR (50 mg / vial) rau kev siv oncology thiab qabzib / lipid metabolism (CAS: 2627-69-2) manufacturers, lwm tus neeg, Hoobkas
