Txoj kev thov
1. Cov lus qhia hloov kho dua tshiab
VIP muaj dej solubility zoo heev. Nws raug nquahu kom rov ua dua nws siv cov dej tsis huv rau kev txhaj tshuaj, tsis muaj menyuam PBS, lossis 1% dilute acetate buffer txhawm rau txhim kho tiav solubility thiab pib stability. Ntxiv cov tshuaj maj mam raws lub raj mis phab ntsa, maj mam swirling ntawm qis ceev. Vigorous vortexing, sonication, thiab siab - kub cua sov yog txwv tsis pub kom tsis txhob peptide saw denaturation thiab adsorption inactivation. Ib qho ntshiab, tsis muaj xim yog qhov qub; qhov tsos ntawm flocculation, turbidity, los yog nag lossis daus qhia tias degradation thiab inactivation, thiab cov tshuaj yuav tsum muab pov tseg tam sim ntawd.
Vim nws luv heev ib nrab-lub neej, nws raug pom zoo kom npaj thiab siv tam sim ntawd, aliquoting ib zaug xwb, thiab tsis txhob rov qab khov -thaw cycles.
2. Kev sim hauv Vitro Cell
Npaj sterile gradient kev daws teeb meem rau macrophage, pa pa epithelium, plab hnyuv epithelium, paj hlwb, thiab cov qauv fibroblast; Feem ntau siv rau kev txheeb xyuas cov kab mob inflammatory, kev tiv thaiv kab mob polarization, apoptosis, kev ua haujlwm tsis zoo, thiab cov txheej txheem fibrosis. Nws raug nquahu kom aliquot cov tshuaj hauv Tshuag thiab khaws cia ntawm -80℃kom tsis txhob muaj kev puas tsuaj sai.
3. Hauv vivo tsiaj sim
Txoj hauv kev tseem ceeb ntawm kev tswj hwm hauv kev tshawb fawb tshawb fawb yog kev txhaj tshuaj subcutaneous thiab txhaj tshuaj intraperitoneal; vim lawv tshem tawm sai heev los ntawm lub cev, cov tsiaj sim feem ntau siv 1-2 koob tshuaj txhua hnub kom tswj tau qhov muaj txiaj ntsig zoo. Nebulization / qhov ntswg tee kuj tseem siv tau rau cov qauv ua pa, nyob ntawm qhov kev sim raws tu qauv, nruj me ntsis ua raws li tus qauv cov koob tshuaj gradient nqis, thiab yuav tsum tau npaj thiab tswj tam sim ntawd.
Daim Ntawv Thov Scenarios thiab Kev Tshawb Fawb Kev Txhim Kho
1. Kab mob o thiab kab mob autoimmune
VIP nthuav tawm dav los tiv thaiv- mob thiab tiv thaiv kab mob hauv cov qauv ntawm rheumatoid mob caj dab (RA), kab mob plab hnyuv (IBD), thiab ntau yam sclerosis (MS):
* Inhibits inflammatory infiltration, pannus tsim, thiab pob txha yaig nyob rau hauv collagen{0}}induced mob caj dab (CIA)
* Downregulates Th1 cytokines (IFN-) thiab upregulates Th2 cytokines (IL-4, IL-10)
* Inhibits matrix metalloproteinase-2 (MMP-2) kev ua
2. Chronic Inflammatory Response Syndrome (CIRS)
Hauv Shoemaker biotoxin-txog kab mob raws tu qauv, VIP yog siv los ua cov kauj ruam kawg (Kauj ruam 12), muab tag nrho cov biomarkers ua ntej (VCS, HLA-DR, TGF- 1, C4a, thiab lwm yam) tau rov qab mus rau qhov qub. Nws lub luag haujlwm yog txhawm rau txhim kho lub cev tiv thaiv kab mob, txhim kho cerebral ntshav txaus perfusion, thiab txhim kho kev txawj ntse.
3. Cov kab mob ua pa
Pulmonary Arterial Hypertension (PAH): Daim ntawv hluavtaws ntawm Aviptadil txo qis cov hlab ntshav siab los ntawm pulmonary vasodilation thiab tau nkag mus rau theem III kev sim tshuaj.
Sarcoidosis thiab mob hawb pob: Kev tswj kev nqus nqus tau raug tshawb nrhiav, siv nws ob lub bronchodilatory thiab tiv thaiv - cov teebmeem inflammatory.
KEVID-19 ntsig txog ARDS: Aviptadil tau txais kev xaiv los ntawm FDA Fast Track, tab sis cov kev sim tom ntej Phase III ua tsis tau raws li qhov tseem ceeb kawg, thiab nws tsis tau txais Kev Tso Cai Siv Thaum Muaj Xwm Ceev.
4. Kab mob plab
Tswj txoj hnyuv du nqaij motility, txhim kho cov tsos mob ntawm irritable plob tsis so tswj syndrome (IBS) thiab inflammatory plob tsis so tswj kab mob (IBD).
Txhawb txoj hnyuv mucosal epithelial kho, tiv thaiv kev ncaj ncees ntawm txoj hnyuv.
Stimulates mucus secretion, tswj txoj hnyuv homeostasis.
FAQ
Q: Qhov kev txiav txim yam tsawg kawg nkaus yog dab tsi?
A: Yam tsawg kawg nkaus kom muaj nuj nqis yog 10 fwj / teeb.
Q: Nws siv sijhawm ntev npaum li cas rau nkoj?
A: Hauv - cov khoom xaj yuav raug xa tuaj hauv 24 teev.
Q: Dab tsi purity theem koj tuaj yeem muab tau?
A: Txheem purity 99%.
Q: Qhov kev pabcuam courier koj siv? A: Koj tuaj yeem xaiv los ntawm FedEx, DHL, UPS, thiab kev pabcuam xa ntawv.
Q: Ntev npaum li cas shipping?
A: Kwv yees li 10-15 hnub.
Q: Koj puas tuaj yeem muab COA (Certificate of Account) daim ntawv tshaj tawm kev soj ntsuam zoo thiab HPLC (High-Performance Computing) qhia?
A: Yog lawm, tag nrho cov khoom raug kuaj xyuas ua ntej ua zaub mov xa tuaj.
Q: Koj puas txhawb OEM hom?
A: OEM branding tau txais kev txhawb nqa, raws li qhov yuav tsum tau ua kom tsawg kawg nkaus kom muaj nuj nqis.
Q: Yuav ua li cas tom qab- kev pabcuam muag khoom?
A: Tom qab cov neeg siv khoom kos npe rau cov khoom, yog tias nws tau lees paub tias qhov teeb meem zoo yog tshwm sim los ntawm peb cov khoom, lawv tuaj yeem txaus siab rau kev hloov pauv dawb lossis nyiaj rov qab. Peb ua raws li lub hauv paus ntsiab lus ntawm kev ua haujlwm thiab lub luag haujlwm, ua tib zoo teb thiab daws txhua yam teeb meem zoo, tsis muaj lub luag haujlwm lossis tsis muaj teeb meem, thiab ua qhov zoo tshaj plaws los tiv thaiv cov cai thiab kev nyiam ntawm peb cov neeg siv khoom.
Q: Txoj kev them nyiaj twg muaj?
A: Peb txhawb nqa kev hloov pauv hauv txhab nyiaj, Bitcoin, Hloov pauv, thiab Xoom.
Cim npe nrov: vip 10mg / vial yog siv los tiv thaiv - kev kho mob ntawm cov kab mob ua pa. cas: 40077-57-4, Tuam Tshoj vip 10mg / vial yog siv rau kev kho mob ntawm cov kab mob ua pa. cas: 40077-57-4 manufacturers, lwm tus neeg, Hoobkas
