GLP-1 yog qhov nrov tsis txaus ntseeg tam sim no, xyaum ua "tus dev saum toj kawg nkaus" hauv thaj chaw ntawm cov metabolism. Yog tias koj koom nrog hauv kev tshawb fawb lossis kev poob phaus thiab tsis tau hnov txog nws, koj yuav txaj muag los hais nyob zoo.
Ua siab ncaj, thaum kuv thawj zaug kawm txog nws, nws zoo li ib tug ntev - tsis nco qab "smart housekeeper" nyob rau hauv peb lub cev. Peb tsuas yog siv cov khoom noj ntawm peb tus kheej xwb, thiab peb lub cev tau hloov kho lub tswv yim zoo rau kev tswj cov piam thaj thiab txo qis qab los noj mov, tsuas yog kom nws tag nrho "tso" los ntawm cov khoom noj niaj hnub no. GLP-1 zoo li coj tus neeg saib xyuas tsev no rov qab rau hauv lub tais.
Tus niam tsev no zoo li cas?
Keeb kwm: Nws yog glucagon-zoo li peptide-1 secreted los ntawm L hlwb hauv plab. Hauv peb lub chaw kuaj mob, peb feem ntau ua haujlwm ntawm nws cov analogues, xws li cov qauv semaglutide nto moo.
Ib nrab-lub neej: Qhov no yog qhov zoo siab tshaj plaws. Ntuj GLP-1 muaj lub neej luv luv hauv lub cev, raug rhuav tshem los ntawm DPP-4 enzyme hauv tsawg dua 2 feeb. Cov kev tshawb fawb niaj hnub no, los ntawm kev hloov cov amino acids (piv txwv li, hloov alanine ntawm txoj hauj lwm 8 nrog Aib), tau txuas nws lub neej mus rau ob peb hnub, lossis ib lub lim tiam.
Daim ntawv: Feem ntau yog cov hmoov lyophilized nyob rau hauv ib lub me me, pob tshab lub raj mis, los yog ib tug premixed txhaj tshuaj (rau kev tshawb fawb siv).
Receptors: Tshwj xeeb tshaj yog tsom rau GLP-1 receptors, feem ntau faib rau hauv pancreas, hlwb, thiab plab hnyuv.
Nws lub peev xwm tshwj xeeb yog dab tsi?
"Kev txawj ntse" cov ntshav qab zib txo qis: Tsis zoo li qee cov tshuaj uas ua rau lub zog brute, nws tsuas yog ua rau lub txiav thaum cov ntshav qab zib siab, ua rau cov hlwb kom zais cov tshuaj insulin ntau dua; ib zaug ntshav qab zib zoo li qub, nws so. Qhov no zoo heev txo qhov kev pheej hmoo ntawm hypoglycemia -nws yog ib qho tseem ceeb heev.
Qab zib "sealing": Qhov no yog qhov uas tib neeg nyiam tshaj plaws los ntawm. Nws tuaj yeem hla cov ntshav- lub hlwb thaiv, ua rau lub hypothalamus ncaj qha rau koj lub hlwb: "Kuv puv, tsis noj." Qhov kev ntshaw rau siab -calorie zaub mov yuav raug tshem tawm tag nrho.
Gastric emptying "brake": Nws slows lub plab motility, ua rau cov zaub mov nyob rau hauv lub plab ntev. Koj yuav hnov zoo tag nrho tom qab noj me ntsis thiab yuav tsis xav noj zaum ob.
Tsis txhob dag los ntawm nws cov txiaj ntsig pom tseeb.
Cov tshuaj muaj zog no muaj nws cov downsides, thiab nws kuj tseem kim heev:
Kev sib ntaus sib tua hauv plab: Thaum koj xub pib siv nws, koj lub cev feem ntau yuav ua rau tsis zoo. Kev xeev siab, ntuav, thiab raws plab yog tshwm sim. Qee tus neeg txawm xav tias xeev siab ntawm qhov tsw ntawm nqaij-koj lub cev yuam kom koj noj nyom.
Muscle poob: Qhov no yog qhov teeb meem loj. Qee qhov hnyav poob yuav yog cov leeg muaj nuj nqis. Yog tsis muaj cov leeg, koj qhov basal metabolic tus nqi poob qis, uas yog qhov tsis zoo.
Nqe barrier: Txawm hais tias nws yog cov khoom siv raw lossis cov khoom tiav, cov txheej txheem synthesis yog complex, yuav tsum tau purity siab, thiab tus nqi tseem pheej pheej yig. Ntev - kev sim mus ntev yog kim heev.
Kev txhawj xeeb zais: Thaum nws zoo li tam sim no, qhov muaj feem cuam tshuam rau lub txiav thiab cov thyroid los ntawm kev siv sijhawm ntev -, nrog rau cov txiaj ntsig rov qab tom qab txiav tawm, yog Damocles 's ntaj dai ntawm peb lub taub hau.
Nws tuaj yeem siv qhov twg?
Obesity thiab Metabolic Syndrome: Qhov no yog nws qhov kev sib ntaus sib tua loj. Nws yog ib qho tseem ceeb rau kev tshawb fawb ntawm cov qauv rog rog thiab insulin tsis kam.
Neuroprotection: Tsis ntev los no, nws tau pom tias muaj qee yam cuam tshuam rau Alzheimer's kab mob qauv, tejzaum nws los ntawm kev txo cov hlwb mob, uas yog qhov xav tsis thoob.
Cov txiaj ntsig ntawm lub plawv: Kev soj ntsuam seb nws puas tuaj yeem txo qhov kev pheej hmoo ntawm myocardial infarction thiab mob stroke tam sim no yog lub ntsiab lus kub.
Yees Duab Yees Duab: Kawm yuav ua li cas nws txwv tsis pub haus cawv thiab nicotine dependence yog ib txoj hauv kev tsis zoo.
Lus Cim Tseem Ceeb:
Txwv tsis pub nruj: Ib zaug ntxiv, qhov no yog kev tshawb fawb reagent loj. Tsis txhob siv kiag li indiscriminately rau lub hom phiaj ntawm lub cev zoo.
Maj mam nce: Hauv kev sim ua qauv, feem ntau yog pib nrog ib koob me me thiab maj mam nce ntxiv kom tso cai rau lub cev ua kom haum; txwv tsis pub, cov tshuaj tiv thaiv yuav hnyav heev.
Kev soj ntsuam ntsuas: Thaum noj tshuaj, ntshav qab zib, pancreatic enzymes, thiab qhov hnyav hloov yuav tsum tau saib xyuas kom zoo. Tshwj xeeb yog mob hnyav
Mob plab tshwm sim, tus kab mob pancreatitis yuav tsum tau xav tias yuav tsum tau ua.
Yuav tsum tau khaws cia nruj me ntsis: Cov khoom no yog rhiab rau cua sov thiab lub teeb. Cov hmoov yuav tsum tau khov, thiab txawm tias tom qab kev npaj, nws yuav tsum tau muab tso rau hauv tub yees. Nws yuav tsum tau siv sai li sai tau, txwv tsis pub nws cov haujlwm yuav txo qis sai.
Kev xav-Kev xav: Yog tias peb pom qhov tseem ceeb tshaj plaws los tswj kev qab los noj mov thiab cov metabolism, tshem tawm tib neeg los ntawm kev xav ntawm "xav noj ntau dua txawm tias thaum puv," peb puas tseem yog tib neeg? Thaum "kev noj mov" tsis yog kev ciaj sia ntxiv lawm tab sis tsuas yog kev sib raug zoo lossis kev ua si, peb lub cev, raug hloov los ntawm kev siv yeeb tshuaj, yeej yeej dhau los ntawm kev hloov pauv, lossis ntxeev siab rau nws? Nws yog ib qho kev xav zoo heev.
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