GDF-8: "Gene Nres" rau cov leeg loj hlob

GDF-8, tseem hu ua myostatin, tau pom thawj zaug los ntawm cov kws tshawb fawb thaum xyoo 1990s. Cov kws tshawb fawb tau xav tsis thoob thaum pom tias kev tshem tawm cov noob no hauv cov nas ua rau lawv loj hlob mus rau hauv cov leeg tsis txaus ntseeg "Hulks." Nyob rau hauv tib neeg, GDF-8 yog protein secreted los ntawm TGF- superfamily, thiab nws lub luag haujlwm tseem ceeb yog ua tus nres ntawm pob txha pob txha loj hlob, tiv thaiv cov leeg tsis muaj zog.

Key Parameters thiab Physical Properties

Recombinant human GDF-8 protein, muaj nyob rau hauv kev tshawb fawb reagent, feem ntau yog nyob rau hauv daim ntawv ntawm ib tug lyophilized hmoov rau txhaj. Nws yog homodimeric protein txuas los ntawm disulfide daim ntawv cog lus, nrog rau qhov hnyav molecular ntawm kwv yees li 25 kDa nyob rau hauv tsis yog - txo cov xwm txheej thiab kwv yees li 13 kDa tom qab txo. High-zoo recombinant GDF-8 muaj qhov purity siab heev, feem ntau ntau dua 95% (raws li tau txiav txim los ntawm SDS-PAGE thiab HPLC). Nws cov amino acid ib ntus tau txais txiaj ntsig zoo thoob plaws ntau hom, nrog ntau dua 95% homology hauv tib neeg, nas, thiab nas. Qhov no txhais tau tias nws cov ntaub ntawv hauv kev sim tsiaj muaj qhov siv tau zoo heev.

**Txoj Cai Cia Cia:**

Raws li cov protein muaj zog heev, GDF-8 kub heev-sensitive thiab yuav tsum tau khaws cia. Unopened lyophilized hmoov yuav tsum khaws cia khov ntawm qhov kub ntawm -20℃thiab -80℃rau ruaj khov rau ntau tshaj ib xyoos. Thaum rov ua dua nrog cov dej tsis muaj menyuam, nws raug nquahu kom aliquot thiab khov hauv qab -20 degree, tsis txhob rov ua kom khov-thaw cycles vim tias cov no tuaj yeem ua rau cov protein ua haujlwm hnyav, ua rau muaj kev tsis ncaj ncees hauv cov ntaub ntawv sim.

**Core Advantages thiab Research Value:**

Rau cov kws tshawb fawb tshawb fawb txog cov leeg nqaij atrophy, rog rog, thiab cov kab mob metabolic, GDF-8 tam sim no yog qhov ntsuas tseem ceeb. Nws yog ib qho tseem ceeb ntawm kev sib txuas ntawm cov leeg nqaij thiab cov pob txha, muab cov qauv lom neeg zoo meej rau kev nkag siab tias tib neeg lub cev tiv thaiv "kev loj hlob dhau." Cov tuam txhab lag luam feem ntau siv nws los ntsuas qhov ua tau zoo ntawm cov tshuaj tshiab cov leeg nqaij loj hlob (xws li myosin inhibitors). Yog tias cov tshuaj tuaj yeem thaiv GDF-8 cov cim qhia tau zoo, nws qhia tau tias muaj peev xwm ua kom cov leeg muaj zog.

Nws yog ib qho tseem ceeb uas yuav tsum nco ntsoov tias feem coob ntawm cov khoom lag luam muaj recombinant GDF-8 cov proteins tau sau meej meej tias yog siv rau kev tshawb fawb nkaus xwb thiab raug txwv nruj heev los ntawm kev siv tib neeg kev kho mob lossis kev txhaj tshuaj ntiag tug.

Cim npe nrov: peptide tshuaj GDF-8 1mg/vial, Tuam Tshoj peptide tshuaj GDF-8 1mg/vial manufacturers, lwm tus neeg, Hoobkas