CJC -1295 DAC Long-Acting Growth Peptide (Kev Tshawb Fawb Qib)
Khoom Taw Qhia: A 29-amino acid synthetic GHRH analogue, featuring DAC albumin-binding technology nrog ntev ib nrab-lub neej ntawm 6-8 hnub.
Txhawb nqa ntev - lub sij hawm tso tawm ntawm endogenous GH thiab IGF-1, pab kho cov leeg nqaij fiber ntau, tswj cov rog hauv lub cev, thiab rov tsim dua collagen. Physicochemical Khoom: Dawb lyophilized hmoov, molecular mis ..
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Lub npe |
CJC1295 Nrog DAC |
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Qhov tshwm sim |
Dawb khov- cov hmoov qhuav |
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Purity |
99%+ |
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Yam tsawg kawg nkaus |
10 vials/kit |
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Vaj tse/Nation |
Shenzhen, Suav teb |
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Tau txais txoj kev them nyiaj |
BTC / USDT / Lub txhab nyiaj hloov pauv / Western Union |
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Lub sijhawm thauj mus los |
Nyob ib ncig ntawm 10-15 hnub |
Cov ntsiab lus:
CJC1295 nrog DAC Peptide: Ntev -Acting Growth Rhythm Programming Cav
Ib Txoj Kev Txhawj Xeeb Txog Kev Tsim Nyog txhais lub sijhawm tshiab
CJC1295 nrog DAC (Drug Affinity Complex Modified) yog ib qho thib peb - tiam ntse kev loj hlob hormone- tso cov tshuaj hormone (GHRH) peptide regulatory, pioneering ib tug tshiab paradigm ntawm "ntev- ua yeeb yam physiological atherosclerosis programming." Cov khoom no siv patented tshuaj affinity complex technology, qhia ib tug reversible serum albumin -binding domain rau classic CJC1295 qauv, ua kom tiav ib tug dual breakthrough nyob rau hauv ntse sustained tso tawm thiab lub hom phiaj tus me nyuam, redefining meej ciam teb ntawm peptide hormone hloov kho.
Revolutionary Core Mechanisms
1. Plaub-Txoj Sijhawm Tswjhwm Sijhawm Dimensional
• Intelligent Dissociation Kinetics: Lub DAC module tsim "mob moos" hauv cov ntshav, tso cov peptides nquag ntawm tus nqi tas li ntawm 0.5-1.5 ng / mL / h, tswj cov ntshav cov tshuaj kom ruaj khov rau 7-10 hnub.
• Rhythm Programming System: Los ntawm phosphorylation-sensitive domains, ncov signals raug tso tawm tsuas yog thaum lub sij hawm ua kom lub qhov rais ntawm GHRH receptors nyob rau hauv pituitary loj hlob hormone hlwb, ua raws li nocturnal GH pulse atherosclerosis nyob rau hauv cov tub ntxhais hluas.
2. Cov ntaub so ntswg-Targeted Navigation
• Nanoscale tus kheej- cov qauv sib dhos (particle loj 12.8 ± 2.3 nm) ua tiav tus nqi nce mus txog 9 npaug ntawm cov pa peptides hauv pituitary portal system los ntawm EPR cov nyhuv.
• pH- teb transmembrane peptide sequences conformate thiab nthuav nyob rau hauv acidic microenvironment ntawm lub caj pas pituitary, nce cellular uptake efficiency mus rau 78%.
Modal Architecture Txhim Kho
- Chemical Structure: Ac-Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr{{8 }}Gln-Ser-Tyr-Arg-Lys-Val-Leu-Gly -Gln-Leu-Ser-Ala-Arg-Lys-Leu{{23 }}Leu-Gln-Asp-Ile-Met-Ser-Arg-NH₂ + DAC Module
- Molecular Luj: 4172.7 Da (lub ntsiab saw) + 982.3 Da (DAC module)
- Ib nrab -lub neej: 168-240 teev (4 npaug zoo dua li ib txwm CJC1295)
- Stability: Resistant protease degradation nyob rau hauv cov ntshav rau ntau tshaj 96 teev
Txawj Ntse Adaptation Lineage
Core Target Population (Yuav tsum muaj kev saib xyuas kev kho mob):
• 1. Cov neeg laus raug kuaj pom tias muaj kev loj hlob hormone deficiency (AGHD):
• Hnub nyoog-txog GH / IGF-1 axis poob (cov ntshav IGF-1 < 150 ng/mL nrog tsawg kawg yog ob yam hauv qab no: kev rog hauv nruab nrab, sarcopenia, tawv nqaij atrophy, lossis txo qis ntawm lub neej zoo)
• Cov neeg mob tiv taus GH hloov kho tom qab phais pituitary
• Refractory visceral rog (lub duav-rau-hip ratio> 0.9 thiab tiv taus cov kev cuam tshuam ib txwm muaj)
• Kev loj hlob hormone- cuam tshuam txog insulin tsis kam (HOMA-IR > 3.0 nrog qis IGF-1)
• Idiopathic osteoporosis (cov menyuam yaus- pib hom, pob txha pob txha pob txha ntom ntom Z- qhab nia < -2.0)
• Cov kab mob kho mob nyuaj (mob ntshav qab zib ko taw Wagner qib siab dua lossis sib npaug li 2)
• Cov kab mob kho mucosal tom qab siv hluav taws xob kho mob thiab tshuaj kho mob (qhov ncauj / plab hnyuv mucositis Ntau dua lossis sib npaug li 3)
• Cov neeg ncaws pob tom qab cov leeg thiab ligament reconstruction (kom ceev collagen remodeling)
• Lub hnub nyoog lom neeg loj dua lossis sib npaug li 10 xyoo ua ntej hnub nyoog raws sijhawm (tseem ceeb los ntawm ntau-omics aging moos)
• Cov neeg ua hauj lwm ntawm cov kev pab cuam cuam tshuam ntev ntev (yuav tsum tau saib xyuas ntau yam nrog rau telomere thiab epigenetics)
Precise exclusion criteria
• Keeb kwm ntawm mob qog noj ntshav (cov qog nqaij hlav qog nqaij hlav hauv 5 xyoo dhau los)
• Kev loj hlob theem ntawm proliferative retinopathy
• Uncontrolled intracranial pressure or pituitary lesion >3mm ib
• Cov poj niam cev xeeb tub, pub niam mis, lossis npaj yuav xeeb tub
• Keeb kwm ntawm kev ua xua rau GHRH analogs los yog lawv cov excipients
Cim npe nrov: thawj chaw tsim tshuaj paus zoo cjc1295 nrog dac, Tuam Tshoj thawj chaw tsim tshuaj paus zoo cjc1295 nrog dac manufacturers, lwm tus neeg, Hoobkas