Raws li kev npaj tsis muaj menyuam, lyophilized hmoov txhaj tshuaj yuav tsum tau tsim nyob rau hauv ib puag ncig tsis muaj menyuam. Lawv Sterility Assurance Level (SAL)- feem ntau yuav tsum tsis pub ntau tshaj 10⁻³- yog lav los ntawm cov txheej txheem tsim tsis muaj menyuam xws li kev ua kom tsis muaj menyuam los ntawm kev pom lossis ncaj qha aseptic filling. Qhov kev ua kom tsis muaj menyuam ntawm cov kab ntau lawm vam khom cov kev ntsuas kev siv tau zoo, suav nrog kev siv cov cuab yeej siv tau, kev saib xyuas ib puag ncig, thiab kev tshaj tawm cov ntaub ntawv pov thawj.
Tej yam tshwm sim cuam tshuam nrog kev siv cov hmoov lyophilized muaj xws li kev tsis haum tshuaj (xws li daim tawv nqaij liab, o, thiab khaus), tawv nqaij qhuav, kab mob (tsim los ntawm kev siv tsis raug), hyperpigmentation, thiab daim tawv nqaij dependency. Yog tias muaj kev tsis xis nyob tom qab siv, ib tus yuav tsum txiav tawm tam sim ntawd thiab nrhiav kev kho mob; Tsis tas li ntawd, nws raug nquahu kom muab cov dej noo thiab kev tiv thaiv lub hnub rau hauv ib qho kev niaj hnub thaum siv cov khoom no.
Cov xwm txheej tau tshaj tawm hauv kev ua lag luam uas tsis muaj npe "lyophilized hmoov" vials raug dag ua lag luam raws li txhaj tshuaj Hom A Botulinum Toxin lossis cov tshuaj zoo sib xws. Raws li kev txheeb xyuas, cov khoom no tau pom tias tsis muaj cov khoom xyaw uas tau hais tseg thiab yog li raug cais raws li cov tshuaj cuav. Tsis tas li ntawd, muaj cov xwm txheej cuam tshuam txog kev muag khoom tsis raug cai- ntawm cov channel tsis raug tso cai- ntawm cov khoom siv "lyophilized hmoov" hnyav- cov tshuaj poob uas tsis muaj daim ntawv pov thawj pom zoo siv tshuaj. Vim tias cov khoom no tsis raug rau qhov txias kom zoo - kev tswj cov saw hlau thaum thauj thiab khaws cia, lawv ua rau muaj kev hem thawj rau tib neeg kev noj qab haus huv.
Cov cai tswj xyuas cov tshuaj thiab cov khoom siv kho mob tswj xyuas nruj heev ntawm cov khoom lyophilized hmoov. Cov neeg tsim khoom tuaj yeem yeem pib rov qab cov khoom lag luam- xws li kev lag luam recombinant humanized collagen lyophilized hmoov- teb rau cov teeb meem uas tau txheeb xyuas thaum kuaj cov khoom lossis hais txog cov khoom siv raw khoom, yog li txo cov kev pheej hmoo.